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For example, information flows into the brain from the heart, the gut, and the vast organ of the skin, carrying vital information about what is happening and whether it is positive, urgent, or challenging. Benzodiazepines work best to decrease the high degree of physical arousal that goes with intense feelings of stress or agitation, and typically they are prescribed in tandem with an SSRI for the first few weeks on that medication. Negative expectations of how things might go wrong in the future lead to bad feelings now. PRACTICE GRATITUDE Most of the things people hope for are things that will give them a better life: more love, better health, more money, and so on.