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Science, philosophy, law, psychology, literature, art, history, and many other disciplines have independently taken up the cause of depression. If one imagines a soul of iron that weathers with grief and rusts with mild depression, then major depression is the startling collapse of a whole structure. Sakado, K., et al. “The Association between the High Interpersonal Sensitivity Type of Personality and a Lifetime History of Depression in a Sample of Employed Japanese Adults.” Psychological Medicine 29, no.